Istradefylline 40 mg/day increased peak concentrations and AUC of CYP3A4 substrates in scientific trials. This effect was not observed with istradefylline twenty mg/working day. Look at dose reduction of delicate CYP3A4 substrates.modafinil will lower the level or result of mavacamten by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Cont
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